Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689961 | 0.92 | KMT2A (0.67) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL1129093 | 0.87 | MEN1 (0.77) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL27881866 | 0.86 | MAPT (0.60) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL16704815 | 0.86 | MAPT (0.60) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL10636593 | 0.86 | NPC1 (0.71) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7427853 | 0.84 | MAPT (0.58) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL14129580 | 0.84 | NPC1 (0.58) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL14852921 | 0.84 | LOXL2 (0.60) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7399657 | 0.84 | NPC1 (0.69) | KMT2ANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL27882017 | 0.84 | MAPT (0.67) | KMT2ANPC1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318389-A1 | AGONISTS OF THE SPHINGOSINE-1 PHOSPHATE RECEPTOR | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318389-A1 | AGONISTS OF THE SPHINGOSINE-1 PHOSPHATE RECEPTOR | S1PR1, S1PR3, S1PR5 | KMT2A 4307/4885NPC1 1484/4885SMN1; SMN2 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.