Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596402 | 0.93 | ACHE (0.46) | ACHECSF1RKDRBCHEKDM4E | |
| SCHEMBL4128096 | 0.92 | ACHE (0.44) | ACHECSF1RKDRBCHEKDM4E | |
| SCHEMBL13596406 | 0.90 | GPR119 (0.42) | ACHECSF1RKDRKDM4EPKM | |
| SCHEMBL4133416 | 0.88 | CSF1R (0.43) | ACHECSF1RKDRGPR119 | |
| SCHEMBL4121981 | 0.87 | GPR119 (0.40) | ACHEGPR119 | |
| SCHEMBL4132649 | 0.86 | GPR119 (0.40) | ACHECSF1RKDRKDM4EPKM | |
| SCHEMBL4125322 | 0.86 | ACHE (0.45) | ACHEBCHEKDM4EPKMGPR119 | |
| SCHEMBL4125892 | 0.86 | GPR119 (0.41) | ACHECSF1RKDRKDM4EPKM | |
| SCHEMBL13597442 | 0.85 | GPR119 (0.40) | ACHECSF1RKDRKDM4EPKM | |
| SCHEMBL4120792 | 0.85 | KDM4E (0.44) | ACHECSF1RKDRBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885CSF1R 628/4885KDR 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.