Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.59 |
| ▸ | CES1 | P23141 | 8/20 | 0.59 |
| ▸ | CES2 | O00748 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666663 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL22525181 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL21422317 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL8898816 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL21257214 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL23386452 | 1.00 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27894617 | 0.98 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL2607813 | 0.98 | FAAH (0.58) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL464492 | 0.91 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL21497513 | 0.89 | FAAH (0.67) | FAAHCES1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | Georg-August-Universität Göttingen Stiftung öffentlichen Rechts (ohne Bereich Humanmedizin) (DE) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | PCNA, DCK, BAD | FAAH 3664/4885CES1 1949/4885CES2 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.