SCHEMBL13596864

C=CCO[C@@H]1OC(COS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H](O[C@@H]2OC(C(=O)O)[C@@H](O[C@@H]3OC(COS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H](O[C@@H]4OC(C(=O)O)C(O)[C@H](O)C4O)C3NC(C)=O)[C@H](O)C2O)C1NC(C)=O

nearest known ligand 0.72

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	MDK	P21741	4/20	0.72

▸	BDNF	P23560	3/20	0.72

▸	PTN	P21246	2/20	0.72

▸	F10	P00742	1/20	0.52

▸	FGF2	P09038	6/20	0.48

▸	BMP2	P12643	2/20	0.43

▸	VEGFA	P15692	2/20	0.43

▸	CXCL12	P48061	2/20	0.43

▸	SHH	Q15465	2/20	0.43

▸	IFNG	P01579	1/20	0.43

▸	PF4	P02776	1/20	0.43

▸	CCL2	P13500	1/20	0.43

▸	SELP	P16109	1/20	0.43

▸	BMP6	P22004	1/20	0.43

▸	CCL11	P51671	1/20	0.43

▸	WNT3A	P56704	1/20	0.43

▸	SELPLG	Q14242	1/20	0.43

▸	HPSE	Q9Y251	2/20	0.43

▸	SERPINC1	P01008	1/20	0.41

▸	F9	P00740	3/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13431419	1.00	MDK (0.72)	MDKBDNFPTNF10FGF2
SCHEMBL13431410	1.00	MDK (0.72)	MDKBDNFPTNF10FGF2
SCHEMBL13431469	0.94	BDNF (0.70)	MDKBDNFPTNF10FGF2
SCHEMBL13431418	0.94	BDNF (0.70)	MDKBDNFPTNF10FGF2
SCHEMBL13431409	0.94	BDNF (0.70)	MDKBDNFPTNF10FGF2
SCHEMBL13431415	0.92	MDK (0.61)	MDKBDNFPTNF10FGF2
SCHEMBL13431412	0.92	MDK (0.61)	MDKBDNFPTNF10FGF2
SCHEMBL13431465	0.92	MDK (0.61)	MDKBDNFPTNF10FGF2
SCHEMBL13596935	0.89	MDK (0.58)	MDKBDNFPTNF10FGF2
SCHEMBL13431447	0.89	MDK (0.58)	MDKBDNFPTNF10FGF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7638503-B2	Small molecule stimulators of neuronal growth	CALIFORNIA INSTITUTE OF TECHNOLOGY (US)	2009-12-29	—	—	US	disclosed