Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDNF | P23560 | 3/20 | 0.70 |
| ▸ | MDK | P21741 | 3/20 | 0.70 |
| ▸ | PTN | P21246 | 2/20 | 0.70 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.45 |
| ▸ | FGF2 | P09038 | 6/20 | 0.44 |
| ▸ | BMP2 | P12643 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 2/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.42 |
| ▸ | SHH | Q15465 | 2/20 | 0.42 |
| ▸ | PF4 | P02776 | 2/20 | 0.42 |
| ▸ | IFNG | P01579 | 1/20 | 0.42 |
| ▸ | CCL2 | P13500 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | BMP6 | P22004 | 1/20 | 0.42 |
| ▸ | CCL11 | P51671 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431418 | 1.00 | BDNF (0.70) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431469 | 1.00 | BDNF (0.70) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431419 | 0.94 | MDK (0.72) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431410 | 0.94 | MDK (0.72) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13596864 | 0.94 | MDK (0.72) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13596935 | 0.89 | MDK (0.58) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431447 | 0.89 | MDK (0.58) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431406 | 0.88 | BDNF (0.69) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431415 | 0.87 | MDK (0.61) | BDNFMDKPTNF10HPSE | |
| SCHEMBL13431465 | 0.87 | MDK (0.61) | BDNFMDKPTNF10HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338387-B2 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100075920-A1 | SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH | NATIONAL SCIENCE FOUNDATION | 2010-03-25 | — | — | US | disclosed |
| US-7638503-B2 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075920-A1 | SMALL MOLECULE STIMULATORS OF NEURONAL GROWTH | BDNF, GAP43, NGF | BDNF 1/4885MDK 624/4885PTN 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.