Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964763 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPSR1CYP3A4CA2KDM4E | |
| SCHEMBL8338767 | 0.84 | IDO1 (0.48) | ALDH1A1CA2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15181144 | 0.81 | CA2 (0.46) | ALDH1A1NPSR1CYP3A4CA2KDM4E | |
| SCHEMBL10272184 | 0.79 | PIK3CA (0.49) | ALDH1A1NPSR1CA2KDM4EMAPT | |
| SCHEMBL11836830 | 0.79 | CYP3A4 (0.57) | ALDH1A1CYP3A4CA2KDM4ECA1 | |
| SCHEMBL13356386 | 0.77 | DAO (0.40) | ALDH1A1NPSR1MAPTKMT2ALMNA | |
| SCHEMBL1403495 | 0.77 | CA2 (0.65) | ALDH1A1NPSR1CA2KDM4ECA1 | |
| SCHEMBL20653537 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CA2CA1 | |
| SCHEMBL22161863 | 0.77 | TSHR (0.46) | ALDH1A1NPSR1CYP3A4MAPTKDM1A | |
| SCHEMBL4685210 | 0.76 | CA2 (0.47) | ALDH1A1NPSR1CYP3A4CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326058-A1 | CaSR Antagonist | JAPAN TOBACCO INC. (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326058-A1 | CaSR Antagonist | CASR, CALCR, CALCRL | ALDH1A1 3748/4885NPSR1 25/4885CYP3A4 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.