SCHEMBL13599602

COC(=O)[C@H](CCCCNC(=O)CSCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(O)[C@H]1OP(=O)(O)O)NC(C)=O

nearest known ligand 0.92

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	EP300	Q09472	4/20	0.92

▸	KAT5	Q92993	2/20	0.92

▸	CREBBP	Q92793	1/20	0.92

▸	NAA50	Q9GZZ1	2/20	0.75

▸	CHAT	P28329	2/20	0.73

▸	NAA40	Q86UY6	5/20	0.72

▸	AURKA	O14965	1/20	0.72

▸	KAT2B	Q92831	1/20	0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Trifluoroacetic Acid SCHEMBL29420158	0.93	EP300 (1.00)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL26165784	0.91	EP300 (0.88)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL17010823	0.90	EP300 (0.86)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL27097665	0.89	EP300 (0.86)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL1370748	0.88	CHAT (0.85)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL30991360	0.88	CHAT (0.85)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL20815907	0.88	CHAT (0.85)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL30361785	0.88	CHAT (0.85)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL19211093	0.88	CHAT (0.87)	EP300KAT5CREBBPNAA50CHAT
SCHEMBL29359401	0.88	CHAT (0.87)	EP300KAT5CREBBPNAA50CHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7626005-B2	Inhibitors of aminoglycoside 6′-N-acetyltransferases, compositions and uses thereof	MCGILL UNIVERSITY (CA)	2009-12-01	—	—	US	disclosed