SCHEMBL27097665

SCHEMBL27097665

CC(C)(COP(=O)(O)OP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCSCC(=O)NCCCCCCCCC[N+](C)(C)C

nearest known ligand 0.86

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 4/20 0.86
▸ KAT5 Q92993 2/20 0.81
▸ CREBBP Q92793 1/20 0.81
▸ CHAT P28329 2/20 0.78
▸ NAA50 Q9GZZ1 2/20 0.78
▸ AURKA O14965 1/20 0.76
▸ KAT2B Q92831 1/20 0.76
▸ NAA40 Q86UY6 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26165784 0.94 EP300 (0.88) EP300KAT5CREBBPCHATNAA50
SCHEMBL17010823 0.92 EP300 (0.86) EP300KAT5CREBBPCHATNAA50
SCHEMBL30361785 0.91 CHAT (0.85) EP300KAT5CREBBPCHATNAA50
SCHEMBL20815907 0.91 CHAT (0.85) EP300KAT5CREBBPCHATNAA50
SCHEMBL1370748 0.91 CHAT (0.85) EP300KAT5CREBBPCHATNAA50
SCHEMBL30991360 0.91 CHAT (0.85) EP300KAT5CREBBPCHATNAA50
SCHEMBL14124932 0.90 EP300 (0.85) EP300KAT5CREBBPCHATNAA50
SCHEMBL30583329 0.90 EP300 (0.82) EP300KAT5CREBBPCHATNAA50
SCHEMBL21068032 0.90 EP300 (0.82) EP300KAT5CREBBPCHATNAA50
SCHEMBL1174543 0.90 EP300 (0.82) EP300KAT5CREBBPCHATNAA50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911372-B2 Compounds SLC10A1, ABCB11, REN EP300 263/4885KAT5 647/4885CREBBP 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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