SCHEMBL30361785

SCHEMBL30361785

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCSCC(=O)O

nearest known ligand 0.86

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CHAT P28329 2/20 0.85
▸ NAA50 Q9GZZ1 2/20 0.85
▸ EP300 Q09472 4/20 0.84
▸ KAT5 Q92993 2/20 0.84
▸ AURKA O14965 2/20 0.84
▸ KAT2B Q92831 1/20 0.84
▸ CREBBP Q92793 1/20 0.79
▸ NAA40 Q86UY6 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370748 1.00 CHAT (0.85) CHATNAA50EP300KAT5AURKA
SCHEMBL30991360 1.00 CHAT (0.85) CHATNAA50EP300KAT5AURKA
SCHEMBL20815907 1.00 CHAT (0.85) CHATNAA50EP300KAT5AURKA
SCHEMBL26700227 0.96 EP300 (0.83) CHATNAA50EP300KAT5AURKA
SCHEMBL28803301 0.96 EP300 (0.83) CHATNAA50EP300KAT5AURKA
SCHEMBL28670397 0.95 CHAT (0.83) CHATNAA50EP300KAT5AURKA
SCHEMBL29366032 0.95 NAA50 (0.84) CHATNAA50EP300KAT5AURKA
SCHEMBL28017929 0.94 EP300 (0.84) CHATNAA50EP300KAT5AURKA
SCHEMBL2112268 0.94 CHAT (0.83) CHATNAA50EP300KAT5AURKA
SCHEMBL18608119 0.94 CHAT (0.87) CHATNAA50EP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4281058-B1 FUNCTIONALIZED LONG-CHAIN DICARBOXYLIC ACIDS, AND THEIR USE FOR TREATMENT OF KIDNEY DISEASES ESPERVITA THERAPEUTICS INC (US) 2026-03-18 — — EP disclosed
US-12396972-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2025-08-26 — — US disclosed
US-20240398737-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2024-12-05 — — US disclosed
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 — — US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 — — US disclosed
US-20230113853-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2023-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230113853-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE AHR, PKD1, CFTR CHAT 750/4885NAA50 1994/4885EP300 1214/4885
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR CHAT 760/4885NAA50 1738/4885EP300 1071/4885
US-12396972-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR CHAT 750/4885NAA50 1994/4885EP300 1214/4885
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease CPT1A, PPARG, PC CHAT 450/4885NAA50 1445/4885EP300 689/4885
US-20240398737-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE AHR, PKD1, CFTR CHAT 750/4885NAA50 1994/4885EP300 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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