SCHEMBL13599863

SCHEMBL13599863

C[Si](C)(CC1CCCCC1)CC1CCC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
ADH1C P00326 2/20 0.37
ADH1A P07327 2/20 0.37
ADH1B P00325 1/20 0.37
ADH4 P08319 1/20 0.37
ADH7 P40394 1/20 0.37
CHRM5 P08912 2/20 0.35
ADRA2C P18825 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
ACHE P22303 1/20 0.34
SIGMAR1 Q99720 3/20 0.33
CYP2B6 P20813 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
SHBG P04278 1/20 0.31
HTR3A P46098 1/20 0.30
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13599864 0.97 CYP1A2 (0.36) CYP1A2ADH1CADH1AADH1BADH4
SCHEMBL13599862 0.97 CYP1A2 (0.42) CYP1A2ADH1CADH1AADH1BADH4
SCHEMBL10356856 0.97 CYP1A2 (0.42) CYP1A2ADH1CADH1AADH1BADH4
SCHEMBL13599865 0.94 CYP1A2 (0.40) CYP1A2ADH1CADH1AADH1BADH4
SCHEMBL13599858 0.94 CYP1A2 (0.32) CYP1A2
SCHEMBL13599861 0.91 CYP1A2 (0.31) CYP1A2
SCHEMBL3895538 0.82 CYP1A2 (0.40) CYP1A2ADH1CADH1AADH1BADH4
SCHEMBL3651570 0.81 SIGMAR1 (0.38) CYP1A2CHRM5ADRA2CCHRM2CHRM4
Hydrochloric Acid SCHEMBL3505547 0.79 SIGMAR1 (0.37) CYP1A2CHRM5ADRA2CCHRM2CHRM4
SCHEMBL5408352 0.79 CYP1A2 (0.36) CYP1A2CHRM5ADRA2CCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638585-B2 Catalyst flow BASF CATALYSTS, LLC (US) 2009-12-29 US disclosed
US-20090286942-A1 CATALYST FLOW BASF CATALYSTS LLC (US) 2009-11-19 US disclosed
US-20090171044-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-02 US disclosed