Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363759 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL380580 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL1111047 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28554233 | 0.86 | GAA (0.48) | — | |
| SCHEMBL5349106 | 0.77 | RECQL (0.61) | — | |
| Butyric Acid SCHEMBL28166159 | 0.77 | FFAR3 (0.54) | — | |
| SCHEMBL124341 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL28528228 | 0.76 | GAA (0.48) | — | |
| SCHEMBL17837031 | 0.76 | — | — | |
| SCHEMBL19380638 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20240228469-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-07-11 | — | — | US | disclosed |
| US-20240217951-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-07-04 | — | — | US | disclosed |
| CN-113453762-B | Pentacyclic heterocyclic compounds | 卫材R&D管理有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20230398223-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
| US-11802107-B2 | Compounds and methods of use | SIGNUM BIOSCIENCES, INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-11723980-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |
| US-20230174467-A1 | COMPOUNDS AND METHODS OF USE | SIGNUM BIOSCIENCES, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| CN-110475474-A | Compound and application method | SIGNUM BIOSCIENCES INC | 2019-11-19 | — | — | CN | disclosed |
| US-20190192668-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-10239889-B1 | Pentacyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-03-26 | — | — | US | disclosed |
| US-20190071452-A1 | PENTACYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-03-07 | — | — | US | disclosed |
| WO-2018132759-A1 | COMPOUNDS AND METHODS USE | SIGNUM BIOSCIENCES, INC. (US) | 2018-07-19 | — | — | WO | disclosed |
| US-20170056419-A1 | Methods and Compositions for Inhibiting Clostridium difficile Spore Germination and Outgrowth | TUFTS UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-9340569-B2 | Methods and compositions for inhibiting clostridium difficile spore germination and outgrowth | TUFTS UNIVERSITY (US) | 2016-05-17 | — | — | US | disclosed |
| US-20110280847-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | TUFTS UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| EP-2367839-A2 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | Tufts University (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010062369-A2 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | TUFTS UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |