Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 7/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8842709 | 1.00 | LAP3 (0.48) | LAP3TSHRFDPSMMP1MMP2 | |
| Phosphoric Acid SCHEMBL8842719 | 1.00 | LAP3 (0.48) | LAP3TSHRFDPSMMP1MMP2 | |
| Phosphoric Acid SCHEMBL27555560 | 0.86 | SLC34A1 (0.40) | LAP3TSHRFDPSMMP1MMP2 | |
| SCHEMBL16959 | 0.80 | — | — | |
| SCHEMBL2335211 | 0.80 | TSHR (0.58) | LAP3TSHR | |
| SCHEMBL14994799 | 0.80 | TSHR (0.58) | LAP3TSHR | |
| Phosphoric Acid SCHEMBL9614686 | 0.80 | LAP3 (0.43) | LAP3TSHRFDPSMMP1MMP2 | |
| Phosphoric Acid SCHEMBL27791847 | 0.80 | LAP3 (0.43) | LAP3TSHRFDPSMMP1MMP2 | |
| Phosphoric Acid SCHEMBL183216 | 0.80 | LAP3 (0.57) | LAP3FDPSGABRR1GABBR2GABBR1 | |
| Phosphoric Acid SCHEMBL159670 | 0.79 | LAP3 (0.48) | LAP3TSHRFDPSMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872712-B1 | Cyclic glycerophosphates and analogs thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-03-29 | — | — | US | claimed |
| EP-1162959-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLIC GLYCEROPHOSPHATES AND ANALOGS THEREOF FOR PROMOTING NEURAL CELL DIFFERENTIATION | YEDA RES & DEV (IL) | 2005-03-09 | — | — | EP | claimed |
| EP-1162979-A2 | CYCLIC GLYCEROPHOSPHATES AND ANALOGS THEREOF | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2001-12-19 | — | — | EP | claimed |
| WO-2000057864-A2 | CYCLIC GLYCEROPHOSPHATES AND ANALOGS THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-10-05 | — | — | WO | claimed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11788055-B2 | Materials and methods for controlling oxidation and reduction in biosynthetic pathways of species of the genera ralstonia and cupriavidus and organisms related thereto | INV NYLON CHEMICALS AMERICAS, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230134936-A1 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | GENOMATICA INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| US-11371046-B2 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors | GENOMATICA, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-10662451-B2 | Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone | GENOMATICA, INC. (US) | 2020-05-26 | — | — | US | disclosed |
| CN-110494461-A | Aqueous polymer dispersions | DOW GLOBAL TECHNOLOGIES LLC | 2019-11-22 | — | — | CN | disclosed |
| US-20190338375-A1 | MATERIALS AND METHODS FOR CONTROLLING OXIDATION AND REDUCTION IN BIOSYNTHETIC PATHWAYS OF SPECIES OF THE GENERA RALSTONIA AND CUPRIAVIDUS AND ORGANISMS RELATED THERETO | INV NYLON CHEMICALS AMERICAS, LLC | 2019-11-07 | — | — | US | disclosed |
| EP-0837630-A4 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | UNIV CALIFORNIA (US) | 1998-11-25 | — | — | EP | disclosed |
| EP-0878508-A2 | Color and hydrolytic stabilization of polycarbonate resins | GENERAL ELECTRIC COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0837630-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5744526-A | USING A MIXTURE OF A PHOSPHITE, PHOSPHINE AND/OR A PHOSPHATE AND TETRAMETHYLENETETRAAMINE; DISCOLORATION INHIBITION; WORKABILITY; MOLDING MATERIALS; BOTTLES | GENERAL ELECTRIC COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0514588-B1 | Novel phosphobetaine and detergent and cosmetic containing the same | KAO CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996039831-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5409705-A | Phosphobetaine and detergent and cosmetic containing the same | KAO CORPORATION (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0514588-A2 | Novel phosphobetaine and detergent and cosmetic containing the same | Kao Corporation (JP) | 1991-11-25 | — | — | EP | disclosed |