Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508615 | 1.00 | F2RL3 (0.45) | F2RL3LMNARECQLDHFRKMT2A | |
| SCHEMBL4508617 | 1.00 | F2RL3 (0.45) | F2RL3LMNARECQLDHFRKMT2A | |
| SCHEMBL13600825 | 0.91 | F2RL3 (0.45) | F2RL3LMNARECQLKMT2AALDH1A1 | |
| SCHEMBL4500077 | 0.90 | LMNA (0.47) | LMNARECQLDHFRKMT2AALDH1A1 | |
| SCHEMBL4500086 | 0.90 | LMNA (0.47) | LMNARECQLDHFRKMT2AALDH1A1 | |
| SCHEMBL4500088 | 0.90 | LMNA (0.47) | LMNARECQLDHFRKMT2AALDH1A1 | |
| SCHEMBL13600852 | 0.86 | MAPT (0.52) | F2RL3LMNARECQLKMT2AALDH1A1 | |
| SCHEMBL13600838 | 0.84 | F2RL3 (0.49) | F2RL3LMNARECQLKMT2AMEN1 | |
| SCHEMBL4511867 | 0.80 | RAB9A (0.44) | LMNARECQLKMT2AMEN1RAB9A | |
| SCHEMBL4518556 | 0.80 | MAPT (0.45) | LMNARECQLALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |