Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 13/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503396 | 1.00 | SIRT3 (0.52) | SIRT3PTPN1EYA3TTRKDM5A | |
| SCHEMBL31314568 | 0.78 | SIRT3 (0.66) | SIRT3PTPN1EYA3TTR | |
| SCHEMBL4503394 | 0.76 | SIRT3 (0.55) | SIRT3PTPN1EYA3TTRKDM5A | |
| SCHEMBL31314684 | 0.74 | SIRT3 (0.74) | SIRT3PTPN1EYA3TTRKDM5A | |
| SCHEMBL1856963 | 0.71 | PTPN1 (0.52) | PTPN1EYA3TTR | |
| SCHEMBL1854472 | 0.68 | PTPN1 (0.51) | PTPN1EYA3TTR | |
| SCHEMBL1854471 | 0.68 | PTPN1 (0.51) | PTPN1EYA3TTR | |
| SCHEMBL2985769 | 0.68 | PTPN1 (0.48) | PTPN1EYA3TTR | |
| SCHEMBL31314611 | 0.68 | SIRT3 (0.65) | SIRT3PTPN1EYA3TTR | |
| SCHEMBL27992957 | 0.66 | EYA3 (0.80) | SIRT3PTPN1EYA3TTRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |