Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 16/20 | 0.55 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314568 | 0.81 | SIRT3 (0.66) | SIRT3EYA3PTPN1TTR | |
| SCHEMBL31314684 | 0.77 | SIRT3 (0.74) | SIRT3EYA3PTPN1TTRKDM5A | |
| SCHEMBL13600960 | 0.76 | SIRT3 (0.52) | SIRT3EYA3PTPN1TTRKDM5A | |
| SCHEMBL4503396 | 0.76 | SIRT3 (0.52) | SIRT3EYA3PTPN1TTRKDM5A | |
| SCHEMBL31314625 | 0.75 | EYA3 (0.67) | SIRT3EYA3PTPN1TTRKDM4A | |
| SCHEMBL27992957 | 0.75 | EYA3 (0.80) | SIRT3EYA3PTPN1TTRKDM4A | |
| SCHEMBL2944813 | 0.74 | PTPN1 (0.69) | SIRT3EYA3PTPN1TTRKDM4A | |
| SCHEMBL31314611 | 0.73 | SIRT3 (0.65) | SIRT3EYA3PTPN1TTR | |
| SCHEMBL2943743 | 0.72 | PTPN1 (0.67) | SIRT3EYA3PTPN1TTRKDM4A | |
| Hydrochloric Acid SCHEMBL9347277 | 0.72 | PTPN1 (0.67) | SIRT3EYA3PTPN1TTRKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | SIRT3 2162/4885EYA3 3724/4885PTPN1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.