Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601034 | 1.00 | F2RL3 (0.49) | F2RL3LTB4RLTB4R2LMNARECQL | |
| SCHEMBL4504529 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2LMNARECQLRXRA | |
| SCHEMBL4504532 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2LMNARECQLRXRA | |
| SCHEMBL4504524 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2LMNARECQLRXRA | |
| SCHEMBL13600838 | 0.84 | F2RL3 (0.49) | F2RL3LMNARECQLRXRACNR2 | |
| SCHEMBL4497419 | 0.84 | LMNA (0.57) | F2RL3LMNARECQLCNR2CYSLTR2 | |
| SCHEMBL13600831 | 0.83 | LTB4R (0.40) | F2RL3LTB4RLTB4R2LMNAPTPN1 | |
| SCHEMBL13600826 | 0.82 | F2RL3 (0.49) | F2RL3LMNARECQLRXRAALDH1A1 | |
| SCHEMBL4491798 | 0.81 | F2RL3 (0.41) | F2RL3LTB4RLTB4R2LMNARECQL | |
| SCHEMBL4496294 | 0.81 | LTB4R (0.41) | F2RL3LTB4RLTB4R2RXRAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |