Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 14/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092540 | 0.81 | NR1H2 (0.34) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL13601366 | 0.72 | NR1H2 (0.33) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1092346 | 0.70 | NR1H2 (0.35) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1091964 | 0.68 | NR1H2 (0.33) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL15832235 | 0.64 | HSD11B1 (0.41) | NR1H3 | |
| SCHEMBL18257253 | 0.63 | RXRA (0.40) | — | |
| SCHEMBL9889527 | 0.63 | FFAR4 (0.41) | — | |
| SCHEMBL18254532 | 0.63 | RXRA (0.39) | — | |
| SCHEMBL30366632 | 0.62 | KDM4E (0.40) | — | |
| SCHEMBL25715298 | 0.62 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144961-A1 | SUBSTITUTED CARBINOL COMPOUND HAVING CYCLIC LINKER | 興和株式会社 (JP) | 2009-12-03 | — | — | WO | disclosed |