Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690705 | 0.80 | EPHX1 (0.40) | ALDH1A1BCHE | |
| SCHEMBL5026392 | 0.79 | ALDH1A1 (0.39) | ALDH1A1BCHEUSP2 | |
| SCHEMBL18957513 | 0.77 | EPHX1 (0.63) | ALDH1A1 | |
| SCHEMBL25866284 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CASP2 | |
| SCHEMBL10508196 | 0.77 | TSHR (0.55) | MEN1KMT2AALDH1A1BCHERECQL | |
| SCHEMBL18430823 | 0.77 | ALDH1A1 (0.38) | ALDH1A1BCHE | |
| SCHEMBL21716170 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1BCHEMTNR1A | |
| SCHEMBL16802993 | 0.76 | TP53 (0.46) | ALDH1A1USP2CASP2 | |
| SCHEMBL14356159 | 0.76 | TP53 (0.46) | ALDH1A1USP2CASP2 | |
| SCHEMBL8125241 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629468-B2 | Neuroprotectants, analgesics or anticonvulsants | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-08 | — | — | US | disclosed |