SCHEMBL10690705

SCHEMBL10690705

O=C(NCCCC1CO1)NCCCC1CO1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.40
ALDH1A1 P00352 1/20 0.40
EPHX2 P34913 10/20 0.39
PRMT1 Q99873 1/20 0.39
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14148258 0.94 EPHX1 (0.43) EPHX1ALDH1A1EPHX2PRMT1
SCHEMBL19361786 0.92 EPHX1 (0.47) EPHX1ALDH1A1EPHX2PRMT1
SCHEMBL18957513 0.88 EPHX1 (0.63) EPHX1ALDH1A1EPHX2
SCHEMBL5026392 0.85 ALDH1A1 (0.39) ALDH1A1ACACBACACABCHE
SCHEMBL18430823 0.83 ALDH1A1 (0.38) ALDH1A1ACACBACACABCHE
SCHEMBL27388641 0.83 KEAP1 (0.44) EPHX1ALDH1A1EPHX2
SCHEMBL13601586 0.80 MEN1 (0.57) ALDH1A1BCHE
SCHEMBL20379484 0.79 ZDHHC20 (0.49) ALDH1A1ACACBACACABCHE
SCHEMBL30912875 0.78 ALDH1A1 (0.41) ALDH1A1EPHX2ACACBACACABCHE
SCHEMBL20380236 0.77 ALDH1A1 (0.42) ALDH1A1ACACBACACABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4728742-A NON-CONJUGATED POLYENES CIBA-GEIGY CORPORATION (US) 1988-03-01 US disclosed