Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601763 | 1.00 | FKBP1A (0.44) | FKBP1AL3MBTL1ALDH1A1LMNAPOLB | |
| SCHEMBL7258683 | 1.00 | FKBP1A (0.44) | FKBP1AL3MBTL1ALDH1A1LMNAPOLB | |
| SCHEMBL13601743 | 0.94 | CHRM2 (0.43) | FKBP1AL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL9657734 | 0.94 | CHRM2 (0.43) | FKBP1AL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL9657740 | 0.94 | CHRM2 (0.43) | FKBP1AL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL13601765 | 0.94 | CHRM2 (0.43) | FKBP1AL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL7262161 | 0.92 | FKBP1A (0.46) | FKBP1A | |
| SCHEMBL13601739 | 0.90 | PPM1B (0.41) | FKBP1A | |
| SCHEMBL13601762 | 0.90 | PPM1B (0.41) | FKBP1A | |
| SCHEMBL7262210 | 0.89 | NR1I2 (0.45) | FKBP1AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |