Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 12/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601739 | 1.00 | PPM1B (0.41) | PPM1BPTPN1PPP1CCFKBP1ACYP3A4 | |
| SCHEMBL26039280 | 0.95 | FKBP1A (0.43) | PPM1BPTPN1PPP1CCFKBP1A | |
| SCHEMBL7258683 | 0.90 | FKBP1A (0.44) | FKBP1A | |
| SCHEMBL13601763 | 0.90 | FKBP1A (0.44) | FKBP1A | |
| SCHEMBL13601742 | 0.90 | FKBP1A (0.44) | FKBP1A | |
| SCHEMBL7262161 | 0.88 | FKBP1A (0.46) | FKBP1A | |
| SCHEMBL9657734 | 0.87 | CHRM2 (0.43) | FKBP1A | |
| SCHEMBL13601765 | 0.87 | CHRM2 (0.43) | FKBP1A | |
| SCHEMBL13601743 | 0.87 | CHRM2 (0.43) | FKBP1A | |
| SCHEMBL9657740 | 0.87 | CHRM2 (0.43) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |