Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 7/20 | 0.33 |
| ▸ | METAP2 | P50579 | 3/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601871 | 0.88 | KDM4E (0.35) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4076092 | 0.88 | KDM4E (0.37) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4072275 | 0.86 | KDM4E (0.37) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL13601883 | 0.86 | KDM4E (0.33) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL30206506 | 0.86 | KDM4E (0.33) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL24950042 | 0.86 | KDM4E (0.33) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL14435226 | 0.86 | KDM4E (0.39) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL951585 | 0.86 | ELANE (0.46) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4080657 | 0.85 | ELANE (0.38) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4079125 | 0.85 | KDM4E (0.32) | KDM4EL3MBTL1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | DDT, ACHE, GAP43 | KDM4E 2264/4885L3MBTL1 1867/4885MEN1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.