Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950042 | 1.00 | KDM4E (0.33) | KDM4EL3MBTL1NR3C2NR3C1PGR | |
| SCHEMBL13601871 | 0.93 | KDM4E (0.35) | KDM4EL3MBTL1NR3C2METAP2MAPT | |
| SCHEMBL14435226 | 0.90 | KDM4E (0.39) | KDM4EL3MBTL1NR3C2METAP2MAPT | |
| SCHEMBL13601883 | 0.90 | KDM4E (0.33) | KDM4EL3MBTL1NR3C2METAP2MAPT | |
| SCHEMBL4079125 | 0.89 | KDM4E (0.32) | KDM4EL3MBTL1NR3C2METAP2MAPT | |
| SCHEMBL4074711 | 0.88 | METAP2 (0.33) | METAP2MAPTTRPA1DHODH | |
| SCHEMBL4077667 | 0.88 | METAP2 (0.33) | KDM4EL3MBTL1NR3C2METAP2MAPT | |
| SCHEMBL4077735 | 0.88 | LIMK1 (0.35) | DHODHTRPV1CYP17A1CYP1A2ELANE | |
| SCHEMBL4073967 | 0.88 | DHODH (0.42) | DHODHTRPV1CYP17A1CYP1A2ELANE | |
| SCHEMBL30206513 | 0.87 | TRPV1 (0.33) | KDM4EL3MBTL1NR3C2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376616-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2024-06-05 | — | — | EP | disclosed |
| CN-117715523-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |