Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906646 | 0.85 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20614594 | 0.85 | NAALAD2 (0.32) | ALDH1A1NAALAD2TSHRL3MBTL1ESR1 | |
| SCHEMBL13601908 | 0.83 | THRB (0.35) | ALDH1A1LMNANAALAD2TSHRL3MBTL1 | |
| SCHEMBL13246588 | 0.81 | NAALAD2 (0.36) | ALDH1A1NAALAD2TSHRESR1CYP3A4 | |
| SCHEMBL23543402 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNANAALAD2 | |
| SCHEMBL24813555 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL22780936 | 0.79 | MAPK1 (0.31) | — | |
| SCHEMBL21933577 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRESR1 | |
| SCHEMBL25148545 | 0.77 | ALDH1A1 (0.37) | ALDH1A1NAALAD2TSHRESR1CYP3A4 | |
| SCHEMBL16329584 | 0.77 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337823-B2 | Modified macromolecule | STARPHARMA PTY LIMITED (AU) | 2012-12-25 | — | — | US | disclosed |
| US-20090324535-A1 | MODIFIED MACROMOLECULE | STARPHARMA PTY LTD (AU) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324535-A1 | MODIFIED MACROMOLECULE | MRPL11, MAX, MRPL38 | ALDH1A1 899/4885LMNA 1304/4885NAALAD2 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.