Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603922 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4MAPTPOLBL3MBTL1 | |
| SCHEMBL13603911 | 0.81 | S1PR4 (0.42) | KMT2APKMALDH1A1MAPTL3MBTL1 | |
| SCHEMBL13603921 | 0.79 | SLC6A2 (0.43) | ALDH1A1POLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL2547749 | 0.77 | GRM5 (0.49) | CHRNB2CHRNA4KMT2AALDH1A1POLB | |
| SCHEMBL29407668 | 0.77 | GRM5 (0.49) | CHRNB2CHRNA4KMT2AALDH1A1POLB | |
| SCHEMBL13603900 | 0.75 | TP53 (0.44) | KMT2ARECQLALDH1A1MAPTKDM4E | |
| SCHEMBL1969238 | 0.75 | USP2 (0.51) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL30454309 | 0.75 | USP2 (0.51) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL16741104 | 0.75 | PTGDR2 (0.53) | KMT2AALDH1A1POLBKDM4EL3MBTL1 | |
| SCHEMBL30680090 | 0.75 | PTGDR2 (0.53) | KMT2AALDH1A1POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638514-B2 | Agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638514-B2 | Agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070142229-A1 | Pesticidally active phenol derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-06-21 | — | — | US | disclosed |
| US-20070142229-A1 | Pesticidally active phenol derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142229-A1 | Pesticidally active phenol derivatives | DDT, QSOX1, CHRM1 | CHRNB2 550/4885CHRNA4 1315/4885KMT2A 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.