Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346908 | 0.91 | KDR (0.48) | PKML3MBTL1GSK3BGSK3AAURKA | |
| SCHEMBL13604079 | 0.88 | MAPK14 (0.46) | PKML3MBTL1ALDH1A1CYP2C9KDR | |
| SCHEMBL1346858 | 0.83 | KDR (0.60) | ALDH1A1CYP2C9KDRMEN1KMT2A | |
| SCHEMBL12133255 | 0.82 | ALDH1A1 (0.61) | PKML3MBTL1GSK3BGSK3AAURKA | |
| SCHEMBL1347067 | 0.80 | MAPK14 (0.48) | PKML3MBTL1ALDH1A1CYP2C9KDR | |
| SCHEMBL1346946 | 0.79 | PKM (0.44) | PKML3MBTL1ALDH1A1CYP2C9KDR | |
| SCHEMBL1344796 | 0.79 | MAPT (0.55) | PKML3MBTL1CYP2C9KDRMEN1 | |
| SCHEMBL1942582 | 0.79 | KDR (0.51) | ALDH1A1CYP2C9KDRMEN1KMT2A | |
| SCHEMBL1939960 | 0.78 | KDR (0.53) | PKML3MBTL1GSK3BGSK3AAURKA | |
| SCHEMBL1940525 | 0.77 | KDR (0.71) | PKML3MBTL1GSK3BGSK3AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128156-A1 | NOVEL OXADIAZOLE DERIVATIVES AND THIADIAZOLE DERIVATIVES HAVING NEOVASCULARIZATION INHIBITING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-02 | — | — | EP | disclosed |