Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562440 | 0.84 | NPC1 (0.50) | PLA2G2AKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL993441 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBABCB1LMNA | |
| SCHEMBL2773966 | 0.80 | KDM4E (0.54) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL27792226 | 0.79 | KDM4E (0.53) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13469244 | 0.78 | KDM4E (0.58) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL1345009 | 0.77 | LRRK2 (0.56) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3230860 | 0.76 | KDM4E (0.61) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL19844014 | 0.76 | KDM4E (0.56) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23292486 | 0.75 | KDM4E (0.55) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4730741 | 0.75 | KDM4E (0.55) | PLA2G2AALDH1A1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128156-A1 | NOVEL OXADIAZOLE DERIVATIVES AND THIADIAZOLE DERIVATIVES HAVING NEOVASCULARIZATION INHIBITING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-02 | — | — | EP | disclosed |