Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688297 | 1.00 | POLB (0.49) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL2889307 | 0.93 | POLB (0.49) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| Monoethanolamine SCHEMBL2889305 | 0.93 | L3MBTL1 (0.43) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| Glycerin SCHEMBL3844851 | 0.92 | POLB (0.45) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL2890516 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL14477954 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL8084202 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL8076306 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL119623 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL14477978 | 0.92 | POLB (0.56) | POLBL3MBTL1SMN1; SMN2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111118901-A | Textile fabric with antibacterial and anti-inflammatory functions | 白中华 | 2020-05-08 | — | — | CN | disclosed |
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-8349215-B2 | Corrosion inhibitors having increased biological degradability and minimized toxicity | CLARIANT FINANCE (BVI) LIMITED (VG) | 2013-01-08 | — | — | US | disclosed |
| US-20120264611-A1 | Pesticide Preparations Containing Derivatives Of Pyrrolidone-4-Carboxylic Acid | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-10-18 | — | — | US | disclosed |
| US-8067651-B2 | 1-alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-29 | — | — | US | disclosed |
| US-20100283011-A1 | Corrosion Inhibitors Having Increased Biological Degradability And Minimized Toxicity | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-11-11 | — | — | US | disclosed |
| US-20100283010-A1 | Corrosion Inhibitors Having Increased Biological Degradability And Minimized Toxicity | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-11-11 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |
| US-20090043146-A1 | 1-Alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043146-A1 | 1-Alkyl-5-oxopyrrolidine-3-carboxylic esters with improved biodegradability | OXER1, CYP1A1, CHRM1 | POLB 952/4885L3MBTL1 3078/4885SMN1; SMN2 3788/4885 |
| US-20120264611-A1 | Pesticide Preparations Containing Derivatives Of Pyrrolidone-4-Carboxylic Acid | DDT, HPD, AGPS | POLB 3374/4885L3MBTL1 2904/4885SMN1; SMN2 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.