Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925165 | 0.90 | MAOB (0.43) | LOXL2LOXENPP3ENPP1AKT2 | |
| Hydrochloric Acid SCHEMBL2926449 | 0.88 | MAOB (0.44) | LOXL2LOXAKT2KCNH2 | |
| SCHEMBL2922147 | 0.86 | KCNH2 (0.35) | ENPP3ENPP1KCNH2ACVR1 | |
| SCHEMBL2925161 | 0.84 | GRM2 (0.40) | ENPP3ENPP1KCNH2GRM2 | |
| SCHEMBL3115300 | 0.81 | DYRK1A (0.48) | ACVR1 | |
| SCHEMBL15884572 | 0.81 | RAF1 (0.44) | ACVR1EGFR | |
| SCHEMBL13175669 | 0.79 | RPS6KA3 (0.36) | KCNH2ACVR1 | |
| SCHEMBL20775145 | 0.78 | LOXL2 (0.44) | LOXL2LOXADRB2PRKCIENPP3 | |
| Hydrochloric Acid SCHEMBL2920921 | 0.78 | KCNH2 (0.35) | KCNH2ACVR1 | |
| Hydrochloric Acid SCHEMBL20774971 | 0.77 | LOXL2 (0.43) | LOXL2LOXADRB2PRKCIENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618959-B2 | Antibacterial agents | SMITHKLINEBEECHAM CORP (US) | 2009-11-17 | — | — | US | disclosed |
| US-7618959-B2 | Antibacterial agents | SMITHKLINEBEECHAM CORP (US) | 2009-11-17 | — | — | US | disclosed |
| US-20070004710-A1 | Antibacterial agents | SMITHKLINE BEECHAM CORPORATION | 2007-01-04 | — | — | US | disclosed |
| US-20070004710-A1 | Antibacterial agents | SMITHKLINE BEECHAM CORPORATION | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004710-A1 | Antibacterial agents | NQO2, NRDC, IFNG | LOXL2 3659/4885LOX 3637/4885ADRB2 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.