SCHEMBL1360804

SCHEMBL1360804

C=Cc1ccccc1O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.34
CYP3A4 P08684 1/20 0.34
NFE2L2 Q16236 3/20 0.33
TRPA1 O75762 1/20 0.33
HPGD P15428 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HDAC8 Q9BY41 1/20 0.32
HTT P42858 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30415589 1.00 ALDH1A1 (0.40) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL1458922 0.82 NFE2L2 (0.38) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL16536268 0.82 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL16537793 0.82 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL7137350 0.81 KMT2A (0.36) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL7133853 0.81 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL9412802 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7132215 0.81 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL7135818 0.81 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1CYP3A4NFE2L2
SCHEMBL1899988 0.81 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1CYP3A4NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005108473-A1 SEMICONDUCTOR NANOPARTICLE-ENCAPSULATING VINYL POLYMER, VINYL POLYMER MIXTURE INCLUDINGTHE SAME, AND PROCESS OF PREPARING THE SAME SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2005-11-17 WO claimed
US-5914219-A Radiation-sensitive mixture and the production of relief structures having improved contrast BASF AKTIENGESELLSCHAFT (DE) 1999-06-22 US claimed
EP-0616258-B1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF AG (DE) 1997-05-21 EP claimed
EP-0605856-B1 Process for the manufacture of p-hydroxystyrene polymers and use thereof BASF AG (DE) 1996-08-28 EP claimed
WO-2024020780-A1 STAR-SHAPED POLYMER, PAINT, COATING, AND METHOD FOR PRODUCING STAR-SHAPED POLYMER DIC CORPORATION (JP) 2024-02-01 WO disclosed
CN-115997158-A Ophthalmic lens 株式会社目立康 2023-04-21 CN disclosed
WO-2022236548-A1 STAR POLYMER, COATING MATERIAL, COATING FILM, AND METHOD FOR PRODUCING STAR POLYMER DIC CORPORATION (JP) 2022-11-17 WO disclosed
CN-107229185-B Energy-sensitive composition, cured product, and method for producing cured product 东京应化工业株式会社 2022-04-15 CN disclosed
CN-114051497-A Chromene compound and photochromic optical article 株式会社德山 2022-02-15 CN disclosed
WO-2021149763-A1 CURABLE COMPOSITION FOR PRODUCTION OF RESIN SHEET 東亞合成株式会社 2021-07-29 WO disclosed
CN-113039075-A Rubber composition, vulcanized rubber, and tire 株式会社普利司通 2021-06-25 CN disclosed
CN-112839989-A Rubber composition, tread rubber, and tire 株式会社普利司通 2021-05-25 CN disclosed
WO-1995021817-A1 SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-08-17 WO disclosed
US-5378585-A Photosensitivity for light sensitive elements MATSUSHITA ELECTRONICS CORPORATION (JP) 1995-01-03 US disclosed
US-5352564-A Copolymer of styrene derivatives, an acid release agent and a dissolution inhibitor containing an unstable acid group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-10-04 US disclosed
US-5290666-A Method of forming a positive photoresist pattern utilizing contrast enhancement overlayer containing trifluoromethanesulfonic, methanesulfonic or trifluoromethaneacetic aromatic diazonium salt HITACHI, LTD. (JP) 1994-03-01 US disclosed
EP-0464614-A2 A composition having sensitivity to light or radiation MATSUSHITA ELECTRONICS CORPORATION (JP) 1992-01-08 EP disclosed
US-5073474-A Organic compound containing acid cleavable group(s) which also forms strong acid on irradiation, positive-working BASF AKTIENGESELLSCHAFT (DE) 1991-12-17 US disclosed
EP-0353600-A2 Aromatic diazonium salt, radiation sensitive composition containing the aromatic diazonium salt and method for formation of pattern using the radiation sensitive composition HITACHI, LTD. (JP) 1990-02-07 EP disclosed
US-4808682-A BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed