Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 11/20 | 0.42 |
| ▸ | TUBB | P07437 | 11/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 11/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 11/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 11/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 11/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 11/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 11/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 11/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 11/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13607980 | 0.83 | KDM4E (0.51) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL4059720 | 0.81 | NPC1 (0.44) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL4059729 | 0.81 | NPC1 (0.44) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13608287 | 0.79 | NPC1 (0.55) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13608189 | 0.79 | PIK3R1 (0.45) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13607964 | 0.77 | TUBB4A (0.48) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13608067 | 0.76 | KDM4E (0.44) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13607768 | 0.76 | TUBB4A (0.54) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL13608033 | 0.75 | GAA (0.43) | NPC1ALDH1A1RAB9AKMT2AKDM4E | |
| SCHEMBL13608032 | 0.74 | RAB9A (0.44) | MEN1NPC1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622479-B2 | Bicyclic derivative, its production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622479-B2 | Bicyclic derivative, its production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |