Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | QPCT | Q16769 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609286 | 0.91 | GAA (0.52) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL291623 | 0.91 | USP2 (0.59) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL13416049 | 0.85 | QPCT (0.62) | NPC1SMN1; SMN2QPCTL3MBTL1MEN1 | |
| SCHEMBL13472650 | 0.81 | KDM4E (0.67) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL49130 | 0.80 | L3MBTL1 (0.66) | NPC1SMN1; SMN2QPCTL3MBTL1ALDH1A1 | |
| SCHEMBL13655177 | 0.80 | SMN1; SMN2 (0.72) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL18544251 | 0.80 | L3MBTL1 (0.69) | NPC1SMN1; SMN2QPCTL3MBTL1MEN1 | |
| SCHEMBL18568234 | 0.79 | QPCT (0.65) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL31283170 | 0.79 | TLR2 (0.56) | GAANPC1SMN1; SMN2QPCTL3MBTL1 | |
| SCHEMBL18317579 | 0.79 | L3MBTL1 (0.68) | NPC1SMN1; SMN2QPCTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | JOHNS HOPKINS UNIVERSOTY (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | HCCS, XPO5, DHX15 | GAA 3851/4885NPC1 2555/4885SMN1; SMN2 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.