Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNA2 | Q15822 | 3/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443246 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TDP1TLR2CHRNB2CHRNA4 | |
| SCHEMBL17830469 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TDP1TLR2CHRNB2CHRNA4 | |
| SCHEMBL24805404 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TDP1TLR2CHRNB2CHRNA4 | |
| SCHEMBL13610212 | 0.95 | ALDH1A1 (0.47) | ALDH1A1TDP1TLR2CHRNB2CHRNA4 | |
| SCHEMBL12996851 | 0.93 | SMN1; SMN2 (0.46) | CHRNB2CHRNA4CHRNA2CHRNB4CHRNA3 | |
| SCHEMBL10273868 | 0.89 | CHRNA3 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL25883074 | 0.89 | CHRNA3 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10273859 | 0.89 | CHRNA3 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL23133816 | 0.87 | SMN1; SMN2 (0.44) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL23168479 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |