Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895034 | 0.87 | SMN1; SMN2 (0.42) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL11724797 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL28774507 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL27175298 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL22857719 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2SPHK2SPHK1 | |
| SCHEMBL13455410 | 0.81 | TSHR (0.38) | ALDH1A1TDP1SMN1; SMN2TSHR | |
| SCHEMBL28030935 | 0.79 | SMN1; SMN2 (0.57) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL8284512 | 0.79 | — | — | |
| SCHEMBL13923572 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL8434237 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |