Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4411984 | 0.98 | PON1 (0.33) | PON1CYP11B1CYP11B2 | |
| Bromide SCHEMBL4414529 | 0.98 | PON1 (0.33) | PON1CYP11B1CYP11B2 | |
| SCHEMBL20516566 | 0.89 | PON1 (0.34) | PON1CYP11B1CYP11B2 | |
| SCHEMBL23698419 | 0.87 | PON1 (0.33) | PON1CYP11B1CYP11B2 | |
| Bromide SCHEMBL1883118 | 0.85 | PON1 (0.32) | PON1CYP11B1CYP11B2 | |
| SCHEMBL23698469 | 0.84 | PON1 (0.38) | PON1CYP11B1CYP11B2 | |
| Bromide SCHEMBL1889460 | 0.82 | PON1 (0.37) | PON1 | |
| SCHEMBL15713803 | 0.82 | XDH (0.36) | PON1 | |
| SCHEMBL23698451 | 0.81 | PON1 (0.46) | PON1 | |
| SCHEMBL23698399 | 0.81 | KMT2A (0.38) | PON1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622543-B2 | Preparing a thermoplastic polyester by contacting macrocyclic polyester oligomer with N-heterocyclic carbene-containing catalyst in the presence of a filler, injection molding | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-24 | — | — | US | disclosed |
| US-20070252311-A1 | Polymerization of macrocyclic polyester oligomers using N-heterocyclic carbene catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-11-01 | — | — | US | disclosed |