Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PON1 | P27169 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516566 | 0.90 | PON1 (0.34) | PON1HTT | |
| Bromide SCHEMBL1658462 | 0.89 | PON1 (0.35) | XDHALDH1A1PON1HTT | |
| SCHEMBL23698469 | 0.85 | PON1 (0.38) | PON1HTT | |
| Bromide SCHEMBL1889460 | 0.83 | PON1 (0.37) | PON1HTT | |
| SCHEMBL13610231 | 0.82 | PON1 (0.33) | PON1 | |
| SCHEMBL23698451 | 0.82 | PON1 (0.46) | PON1HTT | |
| Bromide SCHEMBL4414529 | 0.81 | PON1 (0.33) | PON1 | |
| SCHEMBL23698419 | 0.81 | PON1 (0.33) | PON1 | |
| Iodide SCHEMBL4411984 | 0.81 | PON1 (0.33) | PON1 | |
| Bromide SCHEMBL1882253 | 0.81 | PON1 (0.46) | PON1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917212-B1 | ANTIMICROBIAL AGENTS | UNIV RUTGERS (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-06-28 | — | — | US | disclosed |
| WO-2014074932-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-05-15 | — | — | WO | disclosed |
| US-20130196945-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | CERULEAN PHARMA INC. (US) | 2013-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196945-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY | DDOST, DSC1, SI | XDH 3684/4885ALDH1A1 3595/4885PON1 3730/4885 |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | XDH 366/4885ALDH1A1 1945/4885PON1 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.