Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 14/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362476 | 0.83 | ALDH1A1 (0.41) | GPBAR1 | |
| SCHEMBL1362273 | 0.78 | KMT2A (0.48) | — | |
| SCHEMBL1844491 | 0.77 | PTGS1 (0.44) | PTGS1GPBAR1NR1H3NR1H2 | |
| SCHEMBL13508211 | 0.72 | PTGS1 (0.43) | PTGS1GPBAR1NR1H3NR1H2 | |
| SCHEMBL29183558 | 0.71 | RXFP1 (0.39) | NR1H3NR1H2 | |
| SCHEMBL1766674 | 0.70 | PTGS1 (0.40) | PTGS1GPBAR1NR1H3NR1H2 | |
| SCHEMBL2129697 | 0.67 | MAOA (0.51) | PTGS1NR1H3NR1H2 | |
| SCHEMBL30804865 | 0.66 | ALDH1A1 (0.46) | — | |
| SCHEMBL5356923 | 0.65 | ALDH1A1 (0.45) | — | |
| SCHEMBL1172823 | 0.65 | PBRM1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | PTGS1 1450/4885GPBAR1 2683/4885NR1H3 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.