SCHEMBL13610345

SCHEMBL13610345

CCCCCCCCCCCCCCCCCCNC(=O)C(NC(=O)OCc1ccccc1)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.61
CA5A P35218 1/20 0.61
SIRT2 Q8IXJ6 15/20 0.61
SIRT1 Q96EB6 10/20 0.61
SIRT3 Q9NTG7 6/20 0.61
CA1 P00915 1/20 0.59
MEN1 O00255 1/20 0.58
ALDH1A1 P00352 1/20 0.58
HPGD P15428 1/20 0.58
KMT2A Q03164 1/20 0.58
CTSL P07711 2/20 0.57
CTSS P25774 2/20 0.57
CTSB P07858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7348318 1.00 CA2 (0.61) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL6427219 1.00 CA2 (0.61) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL12555463 0.98 CA2 (0.59) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL2872622 0.98 CA2 (0.59) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL13870510 0.98 CA2 (0.59) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL13870515 0.95 CA2 (0.66) CA2CA5ASIRT2SIRT1SIRT3
SCHEMBL9113504 0.92 CA2 (0.67) CA2CA5ACA1MEN1KMT2A
SCHEMBL25494046 0.91 CTSL (0.71) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL7715048 0.91 CTSL (0.71) SIRT2SIRT1SIRT3MEN1ALDH1A1
SCHEMBL13610346 0.91 CTSL (0.71) SIRT2SIRT1SIRT3MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7623203-B2 Light modulating material FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-7517566-B2 Liquid crystal composition containing at least two gelling agents showing a liquid crystal phase at room temperature, one of which is self-organizing and has an intermolecular binding group-containing unit and a saturated aliphatic hydrocarbon group; improved in whiteness and brightness KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-14 US disclosed
US-7396573-B2 Liquid crystal display element and light-modulating material FUJIFILM CORPORATION (JP) 2008-07-08 US disclosed
US-20080094551-A1 Light modulating material FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20070131903-A1 Dichroic dye and a low molecular weight gelling agent, high display performance FUJIFILM CORPORATION 2007-06-14 US disclosed