SCHEMBL13610411

SCHEMBL13610411

CC(F)(F)C(C)(F)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
KCNN4 O15554 3/20 0.46
MAPK1 P28482 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
PTPN1 P18031 1/20 0.41
CYP3A4 P08684 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
KIF11 P52732 1/20 0.39
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP2B6 P20813 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19319176 0.83 ALDH1A1 (0.52) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL20002043 0.83 ALDH1A1 (0.52) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL17885860 0.83 ALDH1A1 (0.52) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL15721129 0.79 ALDH1A1 (0.48) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL17895323 0.79 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL13741253 0.78 ALDH1A1 (0.52) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL14707464 0.78 ALDH1A1 (0.52) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL17885872 0.77 ALDH1A1 (0.58) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL13554 0.77 ALDH1A1 (0.58) ALDH1A1TSHRKCNN4MAPK1TAAR1
SCHEMBL6342232 0.77 ALDH1A1 (0.58) ALDH1A1TSHRKCNN4MAPK1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140128560-A1 PROCESS TO PREPARE CROSSLINKABLE TRIFLUOROSTYRENE POLYMERS AND MEMBRANES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-08 US disclosed
US-7615300-B2 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology The Board of Regents University and Community College System of Nevada on Behalf of the University of Nevada (US) 2009-11-10 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128560-A1 PROCESS TO PREPARE CROSSLINKABLE TRIFLUOROSTYRENE POLYMERS AND MEMBRANES STOM, PXMP4, TMSB4X ALDH1A1 3564/4885TSHR 2171/4885KCNN4 1398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.