Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342232 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL10910918 | 0.85 | MAPT (0.48) | ALDH1A1TSHRMAPK1ALOX15ESR1 | |
| SCHEMBL17035905 | 0.84 | KIF11 (0.65) | ALDH1A1TSHRMAPK1TAAR1PTPN1 | |
| SCHEMBL12299036 | 0.83 | TSHR (0.40) | ALDH1A1TSHRESR1ESR2CYP3A4 | |
| SCHEMBL3621303 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL17885872 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL23789538 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL10430589 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL9350826 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1TAAR1ALOX15 | |
| SCHEMBL15372301 | 0.78 | LTA4H (0.52) | ALDH1A1TSHRMAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794955-A | Low-water-absorption polyimide resin and preparation method thereof | 长沙新材料产业研究院有限公司 | 2021-05-14 | — | — | CN | claimed |
| US-20040192930-A1 | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2004-09-30 | — | — | US | claimed |
| EP-0923933-B1 | Substituted pyrazolyl benzenesulfonamides for use in the treatment of inflammation | SEARLE & CO (US) | 2002-07-03 | — | — | EP | claimed |
| EP-0923933-A1 | Substituted pyrazolyl benzenesulfonamides for use in the treatment of inflammation | G.D. SEARLE & CO. (US) | 1999-06-23 | — | — | EP | claimed |
| EP-0854723-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-07-29 | — | — | EP | claimed |
| WO-1997011704-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-04-03 | — | — | WO | claimed |
| EP-0731795-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | claimed |
| WO-1995015316-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G. D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | claimed |
| EP-3527600-B1 | ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-119751366-A | Dual-mechanism deep fungal infection resistant medicament | 上海友长医药有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119431313-A | Antifungal compound, preparation method and application thereof | 上海交通大学 | 2025-02-14 | — | — | CN | disclosed |
| EP-4309741-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-01-24 | — | — | EP | disclosed |
| US-20230399287-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-14 | — | — | US | disclosed |
| EP-4275759-A2 | QUINOLINE DERIVATIVES AS CHROMOBOX (CBX) PROTEIN INHIBITORS FOR TREATING CANCER | Dana-Farber Cancer Institute, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| US-5313001-A | Reacting a halogenated aromatic compound with a 1,1-difluoro ethylene compound in presence of palladium catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | disclosed |
| EP-0530208-A1 | PROCESS FOR PRODUCING ALPHA-FLUOROSTYROLS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991016286-A1 | PROCESS FOR PRODUCING α-FLUOROSTYROLS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-31 | — | — | WO | disclosed |
| US-4668830-A | Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-05-26 | — | — | US | disclosed |
| US-4001406-A | BENZENEDISULFONAMIDES AS ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3976691-A | Dialkylaminosulfur trifluorides as fluorinating agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192930-A1 | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation | IL6, HRH4, CCR2 | ALDH1A1 1964/4885TSHR 1806/4885MAPK1 1946/4885 |
| US-20230399287-A1 | NOVEL COMPOUNDS | CNKSR1, RORC, HLA-DRB1 | ALDH1A1 182/4885TSHR 1689/4885MAPK1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.