Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 8/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349499 | 0.83 | AVPR1A (0.60) | AVPR1ANPY5RSIGMAR1 | |
| SCHEMBL2359969 | 0.80 | SIGMAR1 (0.73) | AVPR1ASIGMAR1 | |
| SCHEMBL738397 | 0.77 | AVPR1A (0.50) | AVPR1ANPY5RSIGMAR1 | |
| Hydrochloric Acid SCHEMBL6820620 | 0.76 | AVPR1A (0.49) | AVPR1ANPY5RSIGMAR1 | |
| SCHEMBL4577444 | 0.76 | AVPR1A (0.58) | AVPR1ANPY5R | |
| SCHEMBL30136877 | 0.74 | AVPR1A (1.00) | AVPR1A | |
| SCHEMBL16836272 | 0.74 | AVPR1A (1.00) | AVPR1A | |
| SCHEMBL6054773 | 0.73 | AVPR1A (0.54) | AVPR1ANPY5R | |
| SCHEMBL4367569 | 0.72 | AVPR1A (0.48) | AVPR1ANPY5RSIGMAR1 | |
| SCHEMBL1998588 | 0.72 | NPY5R (0.48) | AVPR1ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629353-B2 | Indol-3-yl-carbonyl-spiro-piperidine derivatives as V1a receptor antagonists | HOFFMAN-LA ROCHE INC. (US) | 2009-12-08 | — | — | US | disclosed |