Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445226 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL13780226 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL13610498 | 0.79 | CYP1A2 (0.35) | RAB9ACYP1A2HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL13610487 | 0.78 | MAPT (0.52) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL6639863 | 0.76 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL13610472 | 0.75 | RAB9A (0.46) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL13610475 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL13610477 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL7825077 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL10562402 | 0.75 | NPC1 (0.59) | SMN1; SMN2NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742635-B1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC (US) | 2018-03-07 | — | — | EP | disclosed |
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |