Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575673 | 0.79 | DAO (0.46) | DAOHSP90AA1HDAC3HDAC1HDAC2 | |
| SCHEMBL2397846 | 0.76 | — | — | |
| SCHEMBL891370 | 0.76 | — | — | |
| SCHEMBL13610498 | 0.74 | CYP1A2 (0.35) | DAOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13610472 | 0.74 | RAB9A (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL980114 | 0.73 | — | — | |
| SCHEMBL11322655 | 0.72 | DAO (0.42) | DAOHSP90AA1HDAC3HDAC1HDAC2 | |
| SCHEMBL6129991 | 0.72 | DAO (0.42) | DAOHSP90AA1HDAC3HDAC1HDAC2 | |
| SCHEMBL7825077 | 0.72 | SMN1; SMN2 (0.50) | CYP1A2CYP2C9CYP2C19RAB9AKDM4E | |
| SCHEMBL1325918 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |