SCHEMBL11575673

SCHEMBL11575673

c1cnc(CSCc2cnccn2)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.46
HSP90AA1 P07900 1/20 0.39
CYP1A2 P05177 3/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 2/20 0.33
VNN1 O95497 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
BAZ2B Q9UIF8 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
MC4R P32245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11322655 0.87 DAO (0.42) DAOHSP90AA1CYP1A2HDAC3HDAC1
SCHEMBL6129991 0.87 DAO (0.42) DAOHSP90AA1CYP1A2HDAC3HDAC1
Ammonia Solution, Strong SCHEMBL10912218 0.85 DAO (0.41) DAOHSP90AA1CYP1A2HDAC3HDAC1
SCHEMBL10857348 0.83 DAO (0.40) DAOHSP90AA1CYP1A2HDAC3HDAC1
SCHEMBL11179089 0.82 DAO (0.39) DAOHSP90AA1CYP1A2HDAC3HDAC1
Hydrochloric Acid SCHEMBL11323936 0.82 L3MBTL1 (0.40) DAOHSP90AA1CYP1A2HDAC3HDAC1
SCHEMBL2397846 0.81
SCHEMBL891370 0.81
SCHEMBL13610495 0.79 DAO (0.40) DAOHSP90AA1CYP1A2HDAC3HDAC1
SCHEMBL6129995 0.79 ALDH1A1 (0.52) DAOCYP1A2KDM4ERAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4105661-A FLAVORANTS FIRMENICH & CIE (CH) 1978-08-08 US claimed
CN-113527789-A Aromatic polyethylene optical cable sheath material for vehicles and preparation method thereof 江阴爱科森博顿聚合体有限公司 2021-10-22 CN disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed