Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624645 | 0.93 | ADRB2 (0.38) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL14802574 | 0.92 | STS (0.33) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL13611324 | 0.89 | PRSS1 (0.44) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL13611323 | 0.86 | CYP4F2 (0.43) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL16270506 | 0.85 | PRSS1 (0.41) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL813523 | 0.85 | PRSS1 (0.42) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL13611330 | 0.84 | CYP4F2 (0.37) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL15375181 | 0.83 | CYP4F2 (0.40) | NPC1MAPTRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL13624644 | 0.81 | HDAC1 (0.40) | NPC1MAPTRAB9AALDH1A1PRSS1 | |
| SCHEMBL14802443 | 0.80 | PRSS1 (0.37) | NPC1MAPTRAB9AALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116866-B2 | Multi-putty adhesive and cement compositions for tissue hemostasis, repair and reconstruction | ABYRX, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200061236-A1 | MULTI-PUTTY ADHESIVE AND CEMENT COMPOSITIONS FOR TISSUE HEMOSTASIS, REPAIR AND RECONSTRUCTION | ORTHOCON, INC. | 2020-02-27 | — | — | US | disclosed |
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130078300-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2013-03-28 | — | — | US | disclosed |
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, L.L.C (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | PUF60, PFAS, UROD | NPC1 963/4885MAPT 3527/4885RAB9A 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.