Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300137 | 0.82 | TRPV1 (0.60) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4553345 | 0.80 | DGAT1 (0.58) | DGAT1EPHX2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL4302935 | 0.79 | DGAT1 (0.62) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4296706 | 0.78 | DGAT1 (0.62) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL13624979 | 0.77 | EPHX2 (0.66) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4251142 | 0.76 | EPHX2 (0.67) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| Hydrochloric Acid SCHEMBL4253231 | 0.75 | EPHX2 (0.66) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL5947865 | 0.75 | EPHX2 (1.00) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4294183 | 0.74 | DGAT1 (0.61) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4295243 | 0.73 | EPHX2 (0.61) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | DLAT, DGAT2, DGAT1 | DGAT1 3/4885EPHX2 1912/4885SMN1; SMN2 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.