Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291779 | 0.85 | DGAT1 (0.67) | DGAT1EPHX2HDAC1HDAC2CYP2C9 | |
| SCHEMBL4294183 | 0.85 | DGAT1 (0.61) | DGAT1EPHX2HDAC1HDAC2CYP2C9 | |
| SCHEMBL4295259 | 0.85 | DGAT1 (0.61) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4289342 | 0.82 | TNFSF11 (0.61) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4300219 | 0.79 | DGAT1 (0.76) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4298316 | 0.79 | DGAT1 (1.00) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4300131 | 0.78 | DGAT1 (0.81) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4302935 | 0.78 | DGAT1 (0.62) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4305430 | 0.77 | DGAT1 (0.79) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL4297509 | 0.77 | DGAT1 (0.79) | DGAT1EPHX2CYP2C9CYP2C19CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | DLAT, DGAT2, DGAT1 | DGAT1 3/4885EPHX2 1912/4885HDAC1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.