Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL441282 | 0.99 | DGAT1 (0.68) | DGAT1 | |
| Trifluoroacetic Acid SCHEMBL4291528 | 0.97 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL4910831 | 0.90 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL407255 | 0.87 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL16527699 | 0.87 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL14305136 | 0.86 | DGAT1 (0.67) | DGAT1 | |
| Hydrochloric Acid SCHEMBL437866 | 0.86 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL4297979 | 0.85 | DGAT1 (0.76) | DGAT1 | |
| SCHEMBL16527833 | 0.85 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL27986789 | 0.85 | DGAT1 (0.64) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286791-A1 | Amide Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286791-A1 | Amide Compounds | DLAT, DGAT2, DGAT1 | DGAT1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.