Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537315 | 0.85 | PABPC1 (0.64) | PABPC1ALDH1A1TSHR | |
| SCHEMBL10781954 | 0.78 | IDO1 (0.52) | IMPDH2IMPDH1ARSLC22A12ALDH1A1 | |
| SCHEMBL3607814 | 0.78 | IMPDH2 (0.47) | IMPDH2IMPDH1ARSLC22A12IDH1 | |
| SCHEMBL29489135 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1ARSLC22A12CA1 | |
| SCHEMBL151936 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1ARSLC22A12CA1 | |
| SCHEMBL5779162 | 0.78 | KDM4E (0.49) | SLC22A12ALDH1A1TSHR | |
| SCHEMBL29506423 | 0.77 | PABPC1 (0.59) | PABPC1ALDH1A1TSHR | |
| SCHEMBL15453221 | 0.77 | PABPC1 (0.59) | PABPC1ALDH1A1TSHR | |
| SCHEMBL5241397 | 0.77 | GAA (0.51) | IMPDH2IMPDH1ARSLC22A12ALDH1A1 | |
| SCHEMBL11193357 | 0.76 | IMPDH2 (0.61) | IMPDH2IMPDH1ARSLC22A12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |