⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611866 | 1.00 | — | — | |
| SCHEMBL8269240 | 0.90 | FFAR4 (0.35) | — | |
| SCHEMBL8269244 | 0.90 | FFAR4 (0.35) | — | |
| SCHEMBL13611630 | 0.90 | FFAR4 (0.35) | — | |
| SCHEMBL8269012 | 0.87 | FFAR1 (0.31) | — | |
| SCHEMBL8269013 | 0.87 | FFAR1 (0.31) | — | |
| SCHEMBL8268251 | 0.87 | — | — | |
| SCHEMBL13513844 | 0.82 | FFAR4 (0.37) | — | |
| SCHEMBL13611611 | 0.72 | FFAR4 (0.42) | — | |
| SCHEMBL13611438 | 0.72 | FFAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638629-B2 | Piperidines and related compounds for treatment of alzheimer's disease | Merck Sharp & Dohme Ltd, (GB) | 2009-12-29 | — | — | US | disclosed |
| US-20080021043-A1 | Piperidines and Related Compounds for Treatment of Alzheimer's Disease | MERCK SHARP & DOHME LTD. (GB) | 2008-01-24 | — | — | US | disclosed |